发明名称 Soluble platinum (II) complex with pyridinecarboxamidine ligand and process for preparing thereof
摘要 In the present invention, there are disclosed platinum (II) complexes with pyridinecarboxamidine ligand of the general formula A, B and C, which exhibit high water solubility, and preparation process of these platinum (II) complexes with pyridinecarboxamidine ligand by reacting o-, m- or p-pyridinecarboxamidine hydrochloride with potassium tetrachloroplatinite in a strongly acidic polar protic medium. Preparation of the above-described substances is characterized by high yields and purity and they are usable in the preparation of novel antitumor medicaments.
申请公布号 CZ306396(B6) 申请公布日期 2017.01.04
申请号 CZ20140000916 申请日期 2014.12.16
申请人 VUAB Pharma a.s. 发明人 Loužilová Tereza;Syslová Kamila;Svoboda Jan;Mikoška Miloš;Kačer Petr;Červený Libor;Maixner Jaroslav;Pažout Richard
分类号 C07F15/00;A61K31/282;A61P35/00;C07D213/58 主分类号 C07F15/00
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