发明名称 HETEROCYCLIC COMPOUND AND HEMATOPOIETIC STEM CELL AMPLIFIER
摘要 An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy useful for treatment of various disorders is provided. An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells containing a compound represented by the formula (I) (wherein X, Y, Z, Ar 1 , R 1 , R 2 , R 3 , R 4 , R 5 , R6 and R 7 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof, which can expand hematopoietic stem cells and/or hematopoietic progenitor cells.
申请公布号 EP2439204(B1) 申请公布日期 2017.01.04
申请号 EP20100783467 申请日期 2010.06.04
申请人 Nissan Chemical Industries, Ltd. 发明人 NISHINO, Taito;IWAMOTO, Shunsuke;MIYAJI, Katsuaki
分类号 C07D333/38;A61K31/4436;A61K31/496;A61K31/5377;A61K38/00;A61K38/22;A61P3/10;A61P7/00;A61P7/06;A61P9/10;A61P21/00;A61P25/00;A61P35/00;A61P35/02;A61P37/04;A61P37/06;A61P43/00;C07D409/12;C07D409/14;C12N5/0789 主分类号 C07D333/38
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