MR-PET cyclic motion gating and correction

摘要

In preparation for acquiring PET image data, subject motion models are built based on physiologic signal monitoring and MR data is collected and used for improved PET imaging. The physiologic signal monitoring is also used during PET imaging, and the acquired MR data is used for prospective or retrospective gating of the PET image acquisition, or in the PET reconstruction for improved correction/imaging.

主权项

1. An imaging system, including:
a magnetic resonance (MR) scanner that scans a region of interest in a subject to generate image data of the region of interest during a physiological cycle; a processor that divides the physiological cycle into a plurality of frames, associates the MR image data to corresponding frames in the physiological cycle, and reconstructs a series of MR images to generate a motion model of the region of interest during the physiological cycle; a positron emission tomography (PET) scanner that collects PET data from the region of interest during the frames of the physiological cycle; a PET reconstruction processor that uses the motion model to generate a PET image in one or more reference frames of the physiological cycle; and a vital signs monitor (VSM) that monitors the physiological cycle in the subject as the MR scanner scans the region of interest; wherein the processor analyzes the motion model to determine an amount of detected motion in each frame of the cyclic physiological signal, identifies a frame in which a smallest amount of motion occurred during the MR scan, and gates the PET scanner to collect data during the identified frame.