Biosensors and methods of preparing same

摘要

A biosensor strip having a low profile for reducing the volume of liquid sample needed to perform an assay. In one embodiment, the biosensor strip includes an electrode support; an electrode arrangement on the electrode support; a cover; a sample chamber; and an incompressible element placed between the cover and the electrode support, the incompressible element providing an opening in at least one side or in the distal end of the sample chamber to provide at least one vent in the sample chamber. In another embodiment, the biosensor strip has an electrode support; an electrode arrangement on the electrode support; a cover; and a sample chamber, the cover having a plurality of openings formed therein, at least one of the openings in register with the sample chamber. The invention further includes methods for preparing such a biosensor strips in a continuous manner.

主权项

1. A glucose sensor, comprising:
a substrate; an electrode positioned on the substrate, the electrode comprising a glucose responsive-enzyme and a mediator disposed thereon; a cover; a spacer layer positioned between the substrate and the cover and forming a sample chamber there between, wherein a portion of the electrode is present in the sample chamber, the sample chamber comprising a proximal end where a sample is introduced into the sample chamber and a distal end toward which the sample flows; and an incompressible element placed between the cover and the spacer layer, said incompressible element positioned only at or near the distal end of the sample chamber and providing at least one vent in the sample chamber at a lateral side of the glucose sensor.