发明名称 |
METHOD FOR THE PROMOTION OF ANGIOGENESIS, VASCULARIZATION, OR VASCULAR REPAIR OR FOR THE INHIBITION OF TUMOR ANGIOGENESIS |
摘要 |
Modulating the function, growth or differentiation of a cell comprises increasing or reducing expression of micro RNA molecule miR-92 in the cell. Independent claims are also included for: (1) a pharmaceutical composition comprising an agent for increasing or reducing miR-92 expression or activity; (2) a molecule comprising 15-22 bases that hybridizes with one of SEQ ID NO:1 to SEQ ID NO:5 (not given in the specification). ACTIVITY : Vasotropic; Antiarteriosclerotic; Cytostatic; Antiinflammatory. MECHANISM OF ACTION : miR-92 enhancer; miR-92 inhibitor. |
申请公布号 |
EP2217704(B1) |
申请公布日期 |
2016.12.07 |
申请号 |
EP20080844273 |
申请日期 |
2008.10.30 |
申请人 |
t2cure GmbH |
发明人 |
DIMMELER, Stefanie;ZEIHER, Andreas, M.;BONAUER, Angelika;URBICH, Carmen |
分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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