发明名称 |
POLYCYCLIC LPA1 ANTAGONIST AND USES THEREOF |
摘要 |
Described herein is the LPA1 antagonist, crystalline form of 1-{4'-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)isoxazol-5-yl]biphenyl-4-yl}cyclopropanecarboxylic acid (Compound 1) and pharmaceutically acceptable salts thereof. Also described is the use of such crystalline forms for treating fibrosis in mammals. |
申请公布号 |
EA024967(B1) |
申请公布日期 |
2016.11.30 |
申请号 |
EA20130090840 |
申请日期 |
2011.12.07 |
申请人 |
AMIRA PHARMACEUTICALS, INC.;BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
BRITTAIN Jason, Edward;SEIDERS Thomas, Jon;KING Christopher, David;ROSSO Victor, W. |
分类号 |
A61K31/42;A61P37/08;C07D261/14 |
主分类号 |
A61K31/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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