发明名称 |
IMMUNOMODULATORY COMPOUNDS FOR THE RESTORATION OF VITAMIN D SENSITIVITY IN VITAMIN D RESISTANT TUMOR CELLS |
摘要 |
Provided herein are methods of restoring vitamin D sensitivity in tumor cells that are vitamin D resistant. Also provided are methods of treating, preventing or managing cancer using an immunomodulatory compound in combination with a vitamin D agent. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods provided herein are also disclosed. |
申请公布号 |
EP2504703(B1) |
申请公布日期 |
2016.11.16 |
申请号 |
EP20100833897 |
申请日期 |
2010.11.24 |
申请人 |
CELGENE CORPORATION |
发明人 |
BROSSEAU, CAROLE;BARTLETT, JUSTIN, BLAKE;DALGLEISH, ANGUS, GEORGE;COLSTON, KAY, WINIFRED;GALUSTIAN, CHRISTINE |
分类号 |
A61K31/593;A61K31/45;A61K31/454;G01N33/50 |
主分类号 |
A61K31/593 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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