| 发明名称 |
MOLECULAR PROFILING OF CD8 T-CELLS IN AUTOCHTHONOUS MELANOMA IDENTIFIES MAF AS DRIVER OF EXHAUSTION |
| 摘要 |
The invention relates to a pharmaceutical composition comprising empowered T cells for use in a method for treating cancer in said patient, wherein said empowered T cells do not express c-Maf or in which the expression or activity of c-Maf is abolished or inhibited. |
| 申请公布号 |
EP3090751(A1) |
申请公布日期 |
2016.11.09 |
| 申请号 |
EP20150166627 |
申请日期 |
2015.05.06 |
| 申请人 |
UNIVERSITÉ DE LAUSANNE |
发明人 |
VERDEIL, GRÉGORY;SPEISER, DANIEL;SCHMITT-VERHULST, ANNE-MARIE |
| 分类号 |
A61K35/17 |
主分类号 |
A61K35/17 |
| 代理机构 |
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