| 发明名称 |
SUBSTITUTED 4-PYRIDONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY |
| 摘要 |
This invention relates to substituted 4-pyridones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other auto-immune and allergic disorders, allograft rejection, and oncological diseases. |
| 申请公布号 |
EP2888249(B1) |
申请公布日期 |
2016.10.26 |
| 申请号 |
EP20130756033 |
申请日期 |
2013.08.22 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
OOST, THORSTEN;FIEGEN, DENNIS;GNAMM, CHRISTIAN;HANDSCHUH, SANDRA;PETERS, STEFAN;ROTH, GERALD JUERGEN |
| 分类号 |
C07D409/12;A61K31/4412;A61P29/00;C07D213/82;C07D401/12;C07D413/12;C07D513/04 |
主分类号 |
C07D409/12 |
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