发明名称 |
COPROCESSED SILICA COATED POLYMER COMPOSITION |
摘要 |
The present invention provides a coprocessed excipient composition and a method of producing the same. The coprocessed excipient comprises vinyl lactam derived polymer and a deagglomerated coprocessing agent. The coprocessing agent is fumed silica, colloidal silica or silicon dioxide. The coprocessed excipient is prepared by a continuous process and has a Brookfield cohesion of less than 0.12 kPa, a bulk density of at least 0.249 gram/milliliter and a flow property as measured by Johanson flow rate number increase from 1.1 to 5.0 fold. |
申请公布号 |
EP2968580(A4) |
申请公布日期 |
2016.10.19 |
申请号 |
EP20140779334 |
申请日期 |
2014.03.12 |
申请人 |
HERCULES INCORPORATED |
发明人 |
TEWARI, DIVYA;TITOVA, YEVGENIYA, A.;BEISSNER, BRAD;DURIG, THOMAS |
分类号 |
A61K47/38;A61K9/20;A61K47/02 |
主分类号 |
A61K47/38 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|