发明名称 Compounds for Positron Emission Tomography
摘要 Described herein are compounds, compositions, and methods for diagnosing and/or monitoring pathogenic disease using positron emission tomography. Also described are conjugates of the formula B-L-P, wherein B is a radical of a targeting agent selected from vitamin receptor binding ligands (such as folate), PSMA binding ligands, or PSMA inhibitors; L is a divalent linker comprising aspartic acid, lysine, or arginine, and P is a radical of an imaging agent or radiotherapy agent, such as a radionuclide or radionuclide containing group, or a radical of a compound capable of binding a radionuclide, such as a metal chelating group.
申请公布号 US2016287731(A1) 申请公布日期 2016.10.06
申请号 US201415035936 申请日期 2014.11.13
申请人 ENDOCYTE, INC. ;PURDUE RESEARCH FOUNDATION 发明人 VLAHOV Iontcho R.;LEAMON Christopher P.;LOW Philip S.;PARHAM Garth L;CHEN Qingshou
分类号 A61K51/04;C07F5/00 主分类号 A61K51/04
代理机构 代理人
主权项
地址 West Lafayette IN US