NUCLEIC ACIDS ENCODING CHIMERIC POLYPEPTIDES FOR LIBRARY SCREENING
摘要
The present disclosure is directed to a library of chimeric polypeptides comprising one or more fragments from the peptidyl-prolyl cis/trans isomerase or FKBP family displaying one or more polypeptides on one or more FKBP members and its use in methods for the screening and selection of constrained peptide surrogates exhibiting binding activity versus predetermined target molecules.
申请公布号
EP2917388(B1)
申请公布日期
2016.10.05
申请号
EP20120784580
申请日期
2012.11.08
申请人
ROCHE DIAGNOSTICS GMBH;F.HOFFMANN-LA ROCHE AG
发明人
CASAGOLDA VALLRIBERA, DAVID;KRONER, FRANK;SCHRAEML, MICHAEL