发明名称 GLYCOSIDASE INHIBITORS AND USES THEREOF
摘要 The invention provides compounds with enhanced permeability for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.
申请公布号 EP2935283(A4) 申请公布日期 2016.10.05
申请号 EP20130868947 申请日期 2013.12.20
申请人 MERCK SHARP & DOHME CORP.;ALECTOS THERAPEUTICS INC. 发明人 SELNICK, HAROLD, G.;LIU, KUN;MCEACHERN, ERNEST, J.;KAUL, RAMESH;WEI, ZHONGYONG;WANG, YAODE;CHANG, JIANG
分类号 C07D513/04;A61K31/429;A61P11/02 主分类号 C07D513/04
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