发明名称 |
SYNTHETIC REGULATION OF GENE EXPRESSION |
摘要 |
Synthetic regulation of gene expression is provided. In some embodiments, synthetic regulatory constructs are provided. In some embodiments, a synthetic regulatory construct expresses a heterologous gene in a selected cell type. In some embodiments, methods of expressing a heterologous gene in a selected cell type are provided. |
申请公布号 |
US2016281107(A1) |
申请公布日期 |
2016.09.29 |
申请号 |
US201615055880 |
申请日期 |
2016.02.29 |
申请人 |
Duke University |
发明人 |
Marengo Matthew S.;Garcia-Blanco Mariano A. |
分类号 |
C12N15/85 |
主分类号 |
C12N15/85 |
代理机构 |
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代理人 |
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主权项 |
1. A synthetic regulatory construct comprising a cell-specific promoter in operable communication with a heterologous gene and a cell-specific exon, wherein the cell-specific promoter and the cell-specific exon are obtained from two distinct genes. |
地址 |
Durham NC US |