发明名称 SYNTHETIC REGULATION OF GENE EXPRESSION
摘要 Synthetic regulation of gene expression is provided. In some embodiments, synthetic regulatory constructs are provided. In some embodiments, a synthetic regulatory construct expresses a heterologous gene in a selected cell type. In some embodiments, methods of expressing a heterologous gene in a selected cell type are provided.
申请公布号 US2016281107(A1) 申请公布日期 2016.09.29
申请号 US201615055880 申请日期 2016.02.29
申请人 Duke University 发明人 Marengo Matthew S.;Garcia-Blanco Mariano A.
分类号 C12N15/85 主分类号 C12N15/85
代理机构 代理人
主权项 1. A synthetic regulatory construct comprising a cell-specific promoter in operable communication with a heterologous gene and a cell-specific exon, wherein the cell-specific promoter and the cell-specific exon are obtained from two distinct genes.
地址 Durham NC US