| 发明名称 |
COMPOSITIONS FOR INDUCING IMMUNE TOLERANCE TO COAGULATION FACTOR PROTEINS |
| 摘要 |
Provided herein are conjugates for inducing tolerance of a coagulation factor protein, wherein the conjugate comprises a coagulation factor protein or an antigenic fragment or variant thereof and a Siglec ligand. Pharmaceutical compositions, methods and kits comprising the conjugates are also provided. |
| 申请公布号 |
US2016279252(A1) |
申请公布日期 |
2016.09.29 |
| 申请号 |
US201414787444 |
申请日期 |
2014.04.27 |
| 申请人 |
BAYER HEALTHCARE LLC |
发明人 |
ASWAD Fred Jullien |
| 分类号 |
A61K47/48;A61K38/37;A61K9/127 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A conjugate for inducing tolerance of a coagulation factor protein, wherein the conjugate comprises a coagulation factor protein or an antigenic fragment or variant thereof and a B cell Siglec ligand. |
| 地址 |
Whippany NJ US |
