NUCLEAR LOCALIZATION OF GLP-1 STIMULATES MYOCARDIAL REGENERATION AND REVERSES HEART FAILURE

摘要

Embodiments of the disclosure provide methods and/or compositions useful for an individual in need of treatment of a cardiac-related medical condition. In particular cases, GLP-1 is employed in a ultrasound targeted microbubble destruction (UTMD) system for delivery to cardiac tissue, thereby stimulating myocardial regeneration and, in at least some cases, reversal of cardiomyopathy.