The invention provides compounds for use in treating microbial infection in an animal. Example compounds include Pyridin-3-ylmethyl (4-((2-aminophenyl)-carbamoyl)benzyl)carbamate (“Entinostat”). The compounds can act via induction of the innate antimicrobial peptide defense system, and stimulation of autophagy.
申请公布号
EP3062784(A1)
申请公布日期
2016.09.07
申请号
EP20140809706
申请日期
2014.10.29
申请人
AKTHELIA PHARMACEUTICALS
发明人
STROMBERG, ROGER;OTTOSON, HAKAN;AGERBERTH, BIRGITTA;GUDMUNDSSON, GUDMUNDUR;MIRAGLIA, ERICA;NYLEN, FRANK