| 摘要 |
The invention provides a composition comprising a plurality of recombinant adenovirus particles, being a recombinant human adenovirus of serotype 5, 26, 34, 35, 48,49 or 50, or a recombinant simian adenovirus, characterized in that the genomes of essentially all adenovirus particles in said composition comprise as the 5' terminal nucleotides the nucleotide sequence: CTATCTAT. The invention also provides methods to produce such compositions. |
