The present invention is directed to indazole compounds which are potent inhibitors of LRRK2 kinase and useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.
申请公布号
EP2964223(A4)
申请公布日期
2016.08.10
申请号
EP20140761162
申请日期
2014.02.27
申请人
MERCK SHARP & DOHME CORP.
发明人
MILLER, MICHAEL;BASU, KALLOL;DEMONG, DUANE;SCOTT, JACK;LI, WEI;STAMFORD, ANDREW;POIRIER, MARC;TEMPEST, PAUL