发明名称 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE
摘要 The present invention provides a compound having the structure: (structurally represented) wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl; R6 is H, OH, or halogen; B is a substituted or unsubstituted heterobicycle, pyridazine, pyrazole, pyrazine, thiadiazole, or triazole, wherein the heterobicycle is other than chloro substituted indole; and the pyrazole, when substituted, is substituted with other than trifluoromethyl, or a pharmaceutically acceptable salt thereof.
申请公布号 EP2968304(A4) 申请公布日期 2016.08.10
申请号 EP20140769462 申请日期 2014.03.13
申请人 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 发明人 PETRUKHIN, KONSTANTIN;CIOFFI, CHRISTOPHER;JOHNSON, GRAHAM;DOBRI, NICOLETA;FREEMAN, EMILY;CHEN, PING;CONLON, MICHAEL;ZHU, LEI
分类号 C07D401/06;A61K31/454;C07D405/14;C07D409/06;C07D471/04;C07D487/04;C07D491/052;C07D495/04;C07D498/04 主分类号 C07D401/06
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