| 发明名称 |
METHOD FOR CULTURING MESENCHYMAL STEM CELLS ACCORDING TO CELL SIZE |
| 摘要 |
A method for culturing mesenchymal stem cells. The method includes isolating mesenchymal stem cells having a size of 8 μm or less and culturing the mesenchymal stem cells in a medium containing calcium and magnesium and under a low oxygen condition. The method can significantly improve the proliferative capacity and differentiation potential of the mesenchymal stem cells. |
| 申请公布号 |
US2016222353(A1) |
申请公布日期 |
2016.08.04 |
| 申请号 |
US201414915680 |
申请日期 |
2014.08.29 |
| 申请人 |
MEDIPOST CO., LTD. |
发明人 |
YANG Yoon-Sun;OH Won II;JIN Hye Jin;KWON Soon-Jae;KIM Miyeon |
| 分类号 |
C12N5/0775;A61K35/28 |
主分类号 |
C12N5/0775 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for culturing mesenchymal stem cells, comprising the steps of:
(1) isolating mesenchymal stem cells having a size of 8 μm or less; and (2) culturing the mesenchymal stem cells in a medium containing 2.1 to 3.8 mM of calcium and 1.0 to 3.0 mM of magnesium under a condition of 2 to 5% oxygen. |
| 地址 |
Seongnam-si, Gyeonggi-do KR |
