| 摘要 |
Described herein are devices, methods and kits for assessing and/or enhancing the accessibility of a subvalvular space of a heart, accessing the subvalvular space of the heart (e.g., to provide access for one or more other devices), and/or positioning one or more devices in the subvalvular space of the heart. The devices described herein may, for example, comprise catheters that may be used to manipulate one or more chordae tendineae, diagnostic catheters having different sizes and/or shapes (e.g., different curvatures), guide catheters having different sizes and/or shapes (e.g., different curvatures), and visualization catheters. In some variations, the devices, methods, and/or kits may be used to visualize a target site, such as a subannular groove of a heart valve. In certain variations, the devices, methods, and/or kits may be used to manipulate chordae tendineae to provide additional space in a ventricle of a heart (e.g., enhancing the accessibility of the ventricle). |
| 主权项 |
1. A shaped catheter configured for advancement into a subvalvular space of a heart comprising:
an elongated member comprising a proximal end, a distal end, and a lumen therethrough, and further comprising an aortic arch curve region defining a first plane, a transition curve region distal to the aortic arch curve region and defining a second plane at a first angle with respect to the first plane, and a valve curve region distal to the transition curve and defining a third plane at a second angle with respect to the second plane, wherein the aortic arch curve region comprises a first preformed curve that corresponds to a curve of an aortic arch, the transition curve region comprises a second preformed curve that corresponds to a curve between an aortic root and a subannular groove of a mitral valve, and the valve curve region comprises a third preformed curve that corresponds to a curve of the subannular groove of the mitral valve. |
