发明名称 PYRIMIDINE COMPOUNDS USEFUL IN THE TREATMENT OF DISEASES MEDIATED BY IKKE AND/OR TBK1 MECHANISMS
摘要 Compounds of the general formula (I) and salts thereof are useful in the treatment of diseases associated with aberrant activity of the protein kinases IKK&egr; and/or TBK-1 in which one of V and W is N, and the other of V and W is C—H; and R1, R2, R3 and R4 are as defined in the specification. The invention also provides uses of the compounds and compositions containing them.
申请公布号 EP2958910(B1) 申请公布日期 2016.08.03
申请号 EP20140706684 申请日期 2014.02.21
申请人 DOMAINEX LIMITED 发明人 NEWTON, GARY KARL;STEWART, MARK RICHARD;PERRIOR, TREVOR ROBERT;CROSBY, STUART RICHARD;HOPKINS, ANNA;NEGOITA-GIRAS, GABRIEL;JENKINS, KERRY
分类号 C07D401/14;A61K31/506;A61P11/06;A61P17/06;A61P25/28;A61P29/00;C07D401/04;C07D405/14;C07D413/14;C07D451/06;C07D471/04;C07D491/10;C07D498/08 主分类号 C07D401/14
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