发明名称 |
PYRIMIDINE COMPOUNDS USEFUL IN THE TREATMENT OF DISEASES MEDIATED BY IKKE AND/OR TBK1 MECHANISMS |
摘要 |
Compounds of the general formula (I) and salts thereof are useful in the treatment of diseases associated with aberrant activity of the protein kinases IKK&egr; and/or TBK-1 in which one of V and W is N, and the other of V and W is C—H; and R1, R2, R3 and R4 are as defined in the specification. The invention also provides uses of the compounds and compositions containing them. |
申请公布号 |
EP2958910(B1) |
申请公布日期 |
2016.08.03 |
申请号 |
EP20140706684 |
申请日期 |
2014.02.21 |
申请人 |
DOMAINEX LIMITED |
发明人 |
NEWTON, GARY KARL;STEWART, MARK RICHARD;PERRIOR, TREVOR ROBERT;CROSBY, STUART RICHARD;HOPKINS, ANNA;NEGOITA-GIRAS, GABRIEL;JENKINS, KERRY |
分类号 |
C07D401/14;A61K31/506;A61P11/06;A61P17/06;A61P25/28;A61P29/00;C07D401/04;C07D405/14;C07D413/14;C07D451/06;C07D471/04;C07D491/10;C07D498/08 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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