发明名称 METHODS AND KITS FOR DIAGNOSING ULCERATIVE COLITIS IN A SUBJECT
摘要 The present invention relates to methods and kits for diagnosing ulcerative colitis in a subject. In particular, the present invention relates to a method for diagnosing ulcerative colitis in a subject comprising the steps consisting of determining in a sample obtained from the subject the expression level of at least one gene selected from the group consisting of ADH4, ADH6, ADHFE1, AKR1A1, AKR7A2, ALDH1A3, ALDH1L1, ALDH7A1, AOX1, BCHE, CBR3, CES1, CYP1B1, CYP2E1, CYP2W1, CYP4F11, CYP51A1, ESD, KCNAB2, COMT, GSTA4, GSTP1, INMT, MGST2, SULT2A1, TPMT, UGT1A4, UGT1A9, UGT2B7, ABCA1, ABCA2, ABCB1, ABCC1, ABCC10, ABCC5, ABCC6, ABCG2, ATP7A, SLC1A3, SLC7A5, SLC10A2, SLC15A1, SLC15A2, SLC19A2, SLC19A3, SLC22A3, SLC28A3, SLC29A2, SLC38A1, SLC38A5, SLC47A1, SLCO2B1, SLCO4C1, ARNT, FOXO1, HIF3A, NCOA2, NCOR2, NR1H3, NR3C1, PPARD, PPARGC1A, RARB, RXRB, and THRB.
申请公布号 EP3049534(A2) 申请公布日期 2016.08.03
申请号 EP20140781111 申请日期 2014.09.26
申请人 INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM);UNIVERSITÉ PARIS DIDEROT (PARIS 7);UNIVERSITÉ DE VERSAILLES SAINT-QUENTIN-EN-YVELINES;ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) 发明人 OGIER-DENIS, ERIC;LADEIRO, YANNICK;TRETON, XAVIER;BOUHNIK, YORAM;DING, YONG-PING
分类号 C12Q1/68 主分类号 C12Q1/68
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