发明名称 PIPERIDINE DERIVATIVES
摘要 The invention relates to compounds of formula where hetaryl I, hetaryl II, R1, R2, R3, R4, m, n, and o are as defined in the specification or to pharmaceutically active acid addition salts thereof. The compounds of formula I are modulators for amyloid beta and thus may be useful for the treatment or prevention of a disease associated with the deposition of beta-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
申请公布号 EP2536710(B1) 申请公布日期 2016.07.13
申请号 EP20110702848 申请日期 2011.02.14
申请人 F.HOFFMANN-LA ROCHE AG 发明人 BAUMANN, KARLHEINZ;FLOHR, ALEXANDER;GOETSCHI, ERWIN;GREEN, LUKE;JOLIDON, SYNESE;KNUST, HENNER;LIMBERG, ANJA;LUEBBERS, THOMAS;THOMAS, ANDREW
分类号 C07D401/14;A61K31/4523;A61P25/28;C07D413/14;C07D417/14;C07D471/04;C07D487/04;C07D498/04 主分类号 C07D401/14
代理机构 代理人
主权项
地址