发明名称 |
1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE DERIVATIVES AS IMMUNOMODULATORS |
摘要 |
The present invention relates to 1,3,4-oxadiazole and 1,3,4-thiadiazole compounds as therapeutic agents capable of inhibiting the programmed cell death 1 (PD1) signalling pathway. The invention also refers to derivatives of the therapeutic agents. The invention also encompasses the use of the said therapeutic agents and derivatives for treatment of disorders via immunopotentiation comprising inhibition of immunosuppressive signal induced due to PD-1, PD-L1, or PD-L2 and therapies using them. |
申请公布号 |
EP3041828(A1) |
申请公布日期 |
2016.07.13 |
申请号 |
EP20140842822 |
申请日期 |
2014.09.05 |
申请人 |
AURIGENE DISCOVERY TECHNOLOGIES LIMITED |
发明人 |
SASIKUMAR, POTTAYIL GOVINDAN NAIR;RAMACHANDRA, MURALIDHARA;NAREMADDEPALLI, SEETHARAMAIAH SETTY SUDARSHAN |
分类号 |
C07D271/06;A61K31/4245;A61K31/433;A61P31/00;A61P35/00;C07D285/08 |
主分类号 |
C07D271/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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