发明名称 |
DEVICE FOR IN-VITRO MODELLING IN-VIVO TISSUES OF ORGANS |
摘要 |
A device (201) for in-vitro modelling in-vivo tissues of organs, comprises: a first body portion (207) with at least one access chamber (213), a second body portion (205) with at least one culturing chamber (221), and a culturing membrane (206) dividing the at least one access chamber (213) from the culturing chamber (221). The device further comprises a third body portion (203) with at least one actuation chamber (220) having at least one limitation cavity, and an actuation membrane (204) dividing the at least one culturing chamber (221) from the at least one actuation chamber (220). With the device according to the invention a robust actuation system can be provided that does not depend on the mechanical properties of the actuation membrane material, nor on the pressure, and that allows to mimic three-dimensional deformations of the tissue, in particular of lung alveoli. |
申请公布号 |
EP3041926(A1) |
申请公布日期 |
2016.07.13 |
申请号 |
EP20140758977 |
申请日期 |
2014.09.05 |
申请人 |
UNIVERSITÄT BERN |
发明人 |
GUENAT, OLIVIER THIERRY;FELDER, MARCEL;STUCKI, ANDREAS;STUCKI, JANICK DANIEL;GEISER, THOMAS |
分类号 |
C12M1/24;C12M1/12;C12M1/34;C12M1/42;C12M3/00 |
主分类号 |
C12M1/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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