| 发明名称 |
PROCESS OF ASYMMETRIC HYDROGENATION OF KETALS AND ACETALS |
| 摘要 |
The present invention relates to a process of the asymmetric hydrogenation of a ketal of an unsaturated ketone or an acetal of an unsaturated aldehyde by molecular hydrogen in the presence of at least one chiral iridium complex. This process yields chiral compounds in a very efficient way and is very advantageous in that the amount of iridium complex can be remarkably reduced. |
| 申请公布号 |
US2016185683(A1) |
申请公布日期 |
2016.06.30 |
| 申请号 |
US201314652562 |
申请日期 |
2013.12.18 |
| 申请人 |
DSM IP ASSETS B.V. |
发明人 |
BONRATH Werner;NETSCHER Thomas;MEDLOCK Jonathan Alan;VERZIJL Gerardus Karel Maria;DE VRIES Andreas Hendrikus Maria |
| 分类号 |
C07B35/02;C07C41/48;B01J31/18;C07D317/12;C07D319/06;C07C41/56;C07C41/58 |
主分类号 |
C07B35/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process of the asymmetric hydrogenation of a ketal of an unsaturated ketone or an acetal of an unsaturated aldehyde by molecular hydrogen in the presence of at least one chiral iridium complex to yield a ketal or acetal having at least one stereogenic carbon centre. |
| 地址 |
Heerlen NL |
