发明名称 SUBSTITUTED PYRROLOPYRIMIDINES AS HDM2 INHIBITORS
摘要 The present invention provides substituted pyrrolopyrimidines as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.
申请公布号 EP2934535(A4) 申请公布日期 2016.06.29
申请号 EP20130865881 申请日期 2013.12.18
申请人 MERCK SHARP & DOHME CORP. 发明人 DINSMORE, CHRISTOPHER;FRADERA LLINAS, FRANCESC XAVIER;KUDALE, AMIT ASHOKRAO;REUTERSHAN, MICHAEL HALE;THOMPSON, CHRISTOPHER FRANCIS;YANG, LIPING;ALTMAN, MICHAEL, D.;BOGEN, STEPHANE, L.;DOLL, RONALD, J.;VOSS, MATTHEW, E.
分类号 C07D487/04;A61K31/519;A61P35/00 主分类号 C07D487/04
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