| 发明名称 |
COMPOSITIONS AND METHODS OF TREATING TUMORS |
| 摘要 |
Methods of treating an individual who has an erb B protein mediated tumor is disclosed. Methods of preventing erb B protein mediated tumors in an individual are disclosed. The methods comprise adminstering to the individual a nucleic acid molecule that encodes a protein that dimerizes with an erb B protein and that is deficient in tyrosine kinase activity. Composition that comprise such nucleic acid molecules including pharmaceutical compositions are disclosed. |
| 申请公布号 |
EP3034093(A1) |
申请公布日期 |
2016.06.22 |
| 申请号 |
EP20150183218 |
申请日期 |
1999.03.04 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
GREENE, MARK I.;O'ROURKE, DONALD M.;MURALI, RAMACHANDRAN;PARK, BYEONG-WOO |
| 分类号 |
A61K39/395;A61K48/00;A61K31/00;A61K38/00;A61K38/17;A61K45/00;A61K51/00;A61P35/00;C07K14/71;C07K16/28;C07K16/32;C12N15/12 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
