发明名称 |
CAMPTOTHECIN DERIVATIVES HAVING ANTI-TUMOR ACTIVITY |
摘要 |
Disclosed are novel camptothecin derivatives having anti-tumor activity (the basic structure thereof is as shown in the figure) and compositions of such compounds and use thereof. The compounds according to the present invention exhibit very good water solubility and stability, show good selectivity among drugs of the same category, and have a very high therapeutic index. Such compounds are promising as therapeutic agents for treating tumors. |
申请公布号 |
EP2695884(B1) |
申请公布日期 |
2016.06.08 |
申请号 |
EP20120768102 |
申请日期 |
2012.04.06 |
申请人 |
NINGBO TEAM PHARMACEUTICAL CO., LTD |
发明人 |
LEI, XIAOGUANG;ZHANG, XIUGUO |
分类号 |
C07D491/22;A61K31/4745;A61P35/00 |
主分类号 |
C07D491/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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