| 发明名称 |
Compounds for the treatment of hypertension and hypertensive end stage renal disease |
| 摘要 |
This disclosure relates to compounds and compositions useful for the treatment of hypertension and hypertensive renal disease. |
| 申请公布号 |
US2016152560(A1) |
申请公布日期 |
2016.06.02 |
| 申请号 |
US201414893802 |
申请日期 |
2014.05.28 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
Tsigelny Igor F.;O'Connor Daniel T.;Kouznetsova Valentina L.;Biswas Nilima |
| 分类号 |
C07C281/18;C07C335/20;C07D233/26 |
主分类号 |
C07C281/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: each X is independently selected from the group consisting of: O and S; R1 and R2 are independently selected from the group consisting of: H, (C1-C6)alkyl, and —C(O)NH(C1-C6)alkyl; R3 is selected from the group consisting of:and
R4 is selected from the group consisting of: wherein R3 and R4 are not the same. |
| 地址 |
Oakland CA US |
