主权项 |
1. A compound of formula (I), wherein A1 and A2 represent direct bond or C(═O), with the proviso that 0 or 1 of A1 and A2 represents C(═O); m and n independently denote 0, 1, 2 or 3, with the proviso that the sum [n+m] is 1, 2, 3 or 4; R1 denotes H, F, Cl, Br, I, CN, CF3, CF2H, CFH2, CO2H, CO2R13, R13, OH, O—R13, NH2, N(H)R13, or N(R13)2; R2 represents 0 to 4 substituents, each independently selected from the group consisting of F, Cl, Br, CN, CF3, CF2H, CFH2, R13, OH, O—R13, NH2, N(H)R13 and N(R13)2; Ar1 represents phenyl or 5- or 6-membered heteroaryl, in each case unsubstituted or substituted with one, two, three or four substituents, independently selected from the group consisting of F, Cl, Br, CN, CF3, CF2H, CFH2, R13 and O—R13;
orC3-6-cycloalkyl or 3 to 7 membered heterocycloalkyl, in each case unsubstituted or mono- or polysubstituted;Ar2 represents phenyl or 5- or 6-membered heteroaryl, wherein said phenyl or said heteroaryl is unsubstituted or mono- or polysubstituted and may be condensed with a 4-, 5-, 6- or 7-membered ring, being carbocyclic or heterocyclic, wherein said condensed ring may be saturated, partially unsaturated or aromatic and is unsubstituted or mono- or polysubstituted;andeach R13 independently of each other denotes
C1-8-alkyl, unsubstituted or mono- or polysubstituted; orC3-6-cycloalkyl or 3 to 7 membered heterocycloalkyl, in each case unsubstituted or mono- or polysubstituted; orC3-6-cycloalkyl or 3 to 7 membered heterocycloalkyl, in each case unsubstituted or mono- or polysubstituted, and in each case connected via a C1-4-aliphatic group, unsubstituted or mono- or polysubstituted;in the form of the free compound or a physiologically acceptable salt thereof or a physiologically acceptable solvate thereof. |