| 摘要 |
PROBLEM TO BE SOLVED: To provide a compound that can be used as an inhibitor of XIa factor or a dual inhibitor of XIa factor and plasma kallikrein.SOLUTION: Provided is a certain crosslinked compound represented by a compound such as 8-oxa-16,18-diaza-tricyclo[13.2.1.0]octadeca-1(17),2,4,6,11,15(18)-hexaene-14-amine, 16,18-diaza-tricyclo[13.2.1.0]octadeca-1(17),2,4,6,15(18)-pentaene-14-amine, or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate thereof.SELECTED DRAWING: None |
