发明名称 Cell-penetrating peptides and uses therof
摘要 Discloses a peptide attached to one or more nucleic acid molecules capable of being internalized into a cell, wherein the peptide molecule a) has a the sequence IREIMEKFGKQPVSLPARRLKLRGRKRRQR (SEQ ID NO: 3); which is internalized into a cell with an efficacy being at least 200% of the internalization efficacy of the TAT peptide having the amino acid sequence GRKKRRQRRRPPQ (SEQ ID NO: 1) and wherein the attachment is accomplished by a linkage selected from the group consisting of a covalent linkage and a non-covalent linkage.
申请公布号 NZ704191(A) 申请公布日期 2016.05.27
申请号 NZ20110704191 申请日期 2011.06.14
申请人 F. HOFFMANN-LA ROCHE AG 发明人 HAAS ALEXANDER;BRINKMANN ULRICH;MAISEL DANIELA
分类号 A61K47/48;C07K14/00 主分类号 A61K47/48
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