| 发明名称 |
RNA Interference-Based Therapeutic Against Anthrax |
| 摘要 |
The present invention includes siRNAs and antibodies that block the interaction between TEM8 and/or CMG2 cell surface proteins and anthrax toxin and methods of treating anthrax exposure with the same. |
| 申请公布号 |
US2016145627(A1) |
申请公布日期 |
2016.05.26 |
| 申请号 |
US201414898179 |
申请日期 |
2014.06.12 |
| 申请人 |
TEXAS TECH UNIVERSITY SYSTEM |
发明人 |
Zeng Mingtao;Arevalo Maria T. |
| 分类号 |
C12N15/113;C07K16/28 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating an anthrax infection in a subject in need of such treatment wherein an siRNA is provided to a subject that targets the cell surface expression of a TEM8 cell surface protein; wherein the siRNA is administered to said subject in a quantity effective to reduce anthrax toxin binding to cells in the subject. |
| 地址 |
Lubbock TX US |
