| 发明名称 |
ANHYDROUS POLYMORPHS OF [(2R,3S,4R,5R)-5-(6-(CYCLOPENTYLAMINO)-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)] METHYL NITRATE AND PROCESSES OF PREPARATION THEREOF |
| 摘要 |
The present invention provides novel anhydrous polymorph forms of 2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl nitrate (Compound A). The present invention also provides processes for preparation of the anhydrous polymorphic forms of compound A. |
| 申请公布号 |
US2016137686(A1) |
申请公布日期 |
2016.05.19 |
| 申请号 |
US201615005697 |
申请日期 |
2016.01.25 |
| 申请人 |
Inotek Pharmaceuticals Corporation |
发明人 |
MCVICAR WILLIAM K. |
| 分类号 |
C07H19/16;C07H1/06 |
主分类号 |
C07H19/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. Crystalline anhydrous polymorph A1 of Compound A characterized by the following crystal data,
C15H20N606; Mr=380.37; Monoclinic crystal system; P21 space group; a=5.546(2) Å; b=7.107(2) Å; c=21.929(9) Å; V=858.8(5) Å3, and Z=2. |
| 地址 |
Lexington MA US |
