发明名称 |
Long-acting coagulation factors and methods of producing same |
摘要 |
Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions comprising the polypeptides and polynucleotides of the invention and methods of using and producing same are also disclosed. |
申请公布号 |
AU2016202829(A1) |
申请公布日期 |
2016.05.19 |
申请号 |
AU20160202829 |
申请日期 |
2016.05.03 |
申请人 |
OPKO BIOLOGICS LTD. |
发明人 |
FIMA, UDI EYAL;HART, GILI |
分类号 |
C07K14/475;A61K38/24;A61K38/36;A61P7/04 |
主分类号 |
C07K14/475 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|