发明名称 |
Method for regulating blood glucose level |
摘要 |
A method for increasing the expression of SIRT1 mRNA and/or decreasing the expression of SOCS3 mRNA, and especially for regulating blood glucose levels in a subject in need thereof is provided. The method comprises administering to the subject an effective amount of an active component selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound of formula (I), and combinations thereof:;wherein X is H or C1-C3 alkyl; one of Y and Z is;
and the other one is H, OH or
;
wherein when Y is
;
Z is
;
R1 to R13 are independently H or OH, and wherein, R1 to R3 are not simultaneously H; R8 and R9 are not simultaneously H. |
申请公布号 |
US9339522(B2) |
申请公布日期 |
2016.05.17 |
申请号 |
US201414289035 |
申请日期 |
2014.05.28 |
申请人 |
SINPHAR PHARMACEUTICAL CO., LTD. |
发明人 |
Kong Zwe-Ling;Ko Fan-Chi;Yeh Ai-Ling |
分类号 |
A61K31/702;A61K36/64;A61K31/7016;C07H15/18;A61K31/7028 |
主分类号 |
A61K31/702 |
代理机构 |
Andrews Kurth LLP |
代理人 |
Wang Ping;Andrews Kurth LLP |
主权项 |
1. A method for regulating blood glucose level in a subject in need thereof, comprising administering to the subject an effective amount of an active component selected from the group consisting of a compound (1), a pharmaceutically acceptable salt of compound (1), and combinations thereof: |
地址 |
Yilan County TW |