发明名称 Solid forms of an antiviral compound
摘要 Crystalline solid forms of the anti-HCV compound (S)-isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2- yl)methoxy)(phenoxy)phosphorylamino)propanoate (Compound I) are described; Also provided are processes of making and methods of using the crystalline forms.
申请公布号 US9340568(B2) 申请公布日期 2016.05.17
申请号 US201414563639 申请日期 2014.12.08
申请人 GILEAD PHARMASSET LLC 发明人 Casteel Melissa Jean;Dashner Kathleen;Jung Hyuk-Jun;Seo Mun Sik;Shi Bing;Wang Fang;Zia Vahid
分类号 A01N43/04;A61K31/70;C07H19/10;A61K31/7052;A61K31/7064;A61K31/706;A61K31/7068;A61K31/7072;C07F9/6558;C07H19/06 主分类号 A01N43/04
代理机构 代理人
主权项 1. A crystalline Compound Icharacterized by an XRPD spectrum comprising peaks at 12.6 and 13.5 °2θ±0.2° 2θ.
地址 Foster City CA US