发明名称 |
Solid forms of an antiviral compound |
摘要 |
Crystalline solid forms of the anti-HCV compound (S)-isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2- yl)methoxy)(phenoxy)phosphorylamino)propanoate (Compound I) are described;
Also provided are processes of making and methods of using the crystalline forms. |
申请公布号 |
US9340568(B2) |
申请公布日期 |
2016.05.17 |
申请号 |
US201414563639 |
申请日期 |
2014.12.08 |
申请人 |
GILEAD PHARMASSET LLC |
发明人 |
Casteel Melissa Jean;Dashner Kathleen;Jung Hyuk-Jun;Seo Mun Sik;Shi Bing;Wang Fang;Zia Vahid |
分类号 |
A01N43/04;A61K31/70;C07H19/10;A61K31/7052;A61K31/7064;A61K31/706;A61K31/7068;A61K31/7072;C07F9/6558;C07H19/06 |
主分类号 |
A01N43/04 |
代理机构 |
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代理人 |
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主权项 |
1. A crystalline Compound Icharacterized by an XRPD spectrum comprising peaks at 12.6 and 13.5 °2θ±0.2° 2θ. |
地址 |
Foster City CA US |