Maintenance of core mammalian body temperature

摘要

The present application relates to methods for maintaining core body temperature in a subject. Heat is applied to peripheral thermoregulatory control tissue of the subject to increase or maintain perfusion of blood in glabrous tissue of the subject, and a warming stimulus is applied to the glabrous tissue. The application of heat to the peripheral thermoregulatory control tissue occurs discretely and simultaneously with application of the warming stimulus to the glabrous tissue, without application of a heating device or a warming device to tissue other than the tissue subjected to the applied heat or to the applied warming stimulus, thereby maintaining the core body temperature of the subject.

主权项

1. A method for maintaining the core body temperature of a subject, comprising:
applying heat from a heating device, wherein the heating device is positioned over the cervical spinal region of the subject, the lumbar spinal region of the subject, or both, such that the heating device applies heat localized to the cervical spinal region of the subject, the lumbar spinal region of the subject, or both, to cause heating of peripheral thermoregulatory control tissue located in the cervical spinal region of the subject, the lumbar spinal region of the subject, or both, wherein the applied localized heat increases or maintains perfusion of blood in glabrous tissue of the subject; and applying a warming stimulus from a warming device to the glabrous tissue; wherein the heat is applied to the peripheral thermoregulatory control tissue located in the cervical spinal region of the subject, the lumbar spinal region of the subject, or both, simultaneously with application of the warming stimulus to the glabrous tissue, thereby maintaining the core body temperature of the subject.