Body cavity prosthesis

摘要

A prosthesis can be configured to be deployed within a body cavity. The prosthesis has an expandable frame, a plurality of proximal anchors, and a plurality of distal anchors, where the various anchors are connected to the frame. Radial expansion of the frame can cause the ends of the proximal anchors and the ends of the distal anchors to draw closer together.

主权项

1. A prosthesis configured to be deployed within a patient's mitral valve having a mitral annulus, the prosthesis comprising:
an expandable frame comprising a proximal end and a distal end and a longitudinal axis extending therethrough, the frame configured to radially expand and collapse for deployment within the mitral valve; a plurality of proximal anchors each connected to the frame so that when the frame is in an expanded configuration, outermost ends of the proximal anchors are positioned radially outward from the frame and configured to be positioned on an atrial side of the mitral annulus; and a plurality of distal anchors each connected to the frame so that when the frame is in an expanded configuration, the distal anchors curve radially outwardly and have outermost ends that are positioned radially outward from the frame and extend generally proximally so that the outermost ends of the distal anchors are proximal to where the distal anchors connect to the frame, the plurality of distal anchors each comprising a tip that extends proximally and substantially parallel to the longitudinal axis of the frame when the frame is in an expanded configuration, the distal anchors configured to be positioned on a ventricular side of the mitral annulus; a valve body attached to the frame, wherein the valve body can move between (i) an open position wherein blood can flow from the proximal end toward the distal end to allow blood to flow from the left atrium to the left ventricle, and (ii) a closed position which blocks blood from flowing from the distal end toward the proximal end to block blood from flowing from the left ventricle to the left atrium; wherein the outermost ends of the proximal anchors are circumferentially offset from the outermost ends of the distal anchors when the frame is in an expanded configuration; and wherein the frame is configured such that radial expansion of the frame causes the proximal anchors and the distal anchors to draw closer together.