| 发明名称 | Activation of human antigen-presenting cells through dendritic cell lectin-like oxidized LDL receptor-1 (LOX-1) | ||
| 摘要 | The present invention includes compositions and methods for targeting the LOX-1 receptor on immune cells and uses for the anti-LOX-1 antibodies. | ||
| 申请公布号 | US9339556(B2) | 申请公布日期 | 2016.05.17 |
| 申请号 | US201313927437 | 申请日期 | 2013.06.26 |
| 申请人 | Baylor Research Institute | 发明人 | Banchereau Jacques F.;Oh SangKon;Zurawski Gerard;Zurawski Sandra;Li Dapeng |
| 分类号 | C07K16/00;C07K17/00;C07K17/14;C12P21/08;A61K47/48;C07K16/28;A61K39/00 | 主分类号 | C07K16/00 |
| 代理机构 | Norton Rose Fulbright US LLP | 代理人 | Norton Rose Fulbright US LLP |
| 主权项 | 1. A LOX-1-specific antibody linked to one or more antigens; wherein the antibody comprises the variable regions of SEQ ID NOS:7 and 8. | ||
| 地址 | Dallas TX US | ||