摘要 |
Compounds that modulate the oxidoreductase enzyme indoleamine 2,3- dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided. |
申请人 |
FLEXUS BIOSCIENCES, INC. |
发明人 |
BECK, HILARY PLAKE;JAEN, JUAN CARLOS;OSIPOV, MAKSIM;POWERS, JAY PATRICK;REILLY, MAUREEN KAY;SHUNATONA, HUNTER PAUL;WALKER, JAMES ROSS;ZIBINSKY, MIKHAIL;BALOG, JAMES AARON;WILLIAMS, DAVID K.;MARKWALDER, JAY A.;SEITZ, STEVEN P.;CHERNEY, EMILY CHARLOTTE;ZHANG, LIPING;SHAN, WEIFANG;GUO, WEIWEI;HUANG, AUDRIS |