发明名称 |
ANTAGONIST ANTI-IL-7 RECEPTOR ANTIBODIES AND METHODS |
摘要 |
- 97 The present invention provides antagonizing antibodies that bind to interleukin-7 receptor (IL-7R). The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acids. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof for the treatment and/or prevention of type 2 diabetes and immunological disorders, including type 1 diabetes, multiple sclerosis, rheumatoid arthritis, graft-versus-host disease, and lupus. |
申请公布号 |
AU2014201648(B2) |
申请公布日期 |
2016.05.12 |
申请号 |
AU20140201648 |
申请日期 |
2014.03.19 |
申请人 |
RINAT NEUROSCIENCE CORP. |
发明人 |
LIN, CHIA-YANG;LEE, LI-FEN;ZHAI, WENWU |
分类号 |
C07K16/28;A61K39/395;A61P3/10;A61P37/00;A61P37/06;C12N15/13 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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