发明名称 |
ENZYMES AND METHODS FOR STYRENE SYNTHESIS |
摘要 |
The subject technology generally relates to biosynthesis of styrene. Certain embodiments of the subject technology is based, in part, on the recognition that phenylalanine can be converted to styrene by a two-step pathway of deamination and decarboxylation, with trans-cinnamic acid (tCA) as the intermediate. Two types of enzymes are directly involved in this process, phenylalanine ammonia lyase (PAL), which converts phenylalanine to tCA, and cinnamic acid decarboxylase, which coverts tCA to styrene. Host cells expressing these two types of enzymes can be cultured in bioreactor to produce styrene from renewable substrates such as glucose. |
申请公布号 |
EP2864491(A4) |
申请公布日期 |
2016.05.11 |
申请号 |
EP20130806939 |
申请日期 |
2013.06.21 |
申请人 |
PHYTOGENE, INC. |
发明人 |
BHUIYA, MOHAMMAD WADUD;CHEN, HUI;CAI, XIANPENG;HAN, JIXIANG;YU, XIAODAN |
分类号 |
C12P7/40;C12N1/26;C12N9/00;C12N9/88;C12N15/62;C12P5/00;C12P7/22 |
主分类号 |
C12P7/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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