发明名称 Method for producing structured microcarriers
摘要 The present invention relates to a method for producing microcarriers, the method comprising the steps of providing a wafer having a bottom layer, a top layer and an insulating layer, structuring the top layer to define at least one three-dimensional structure on the top surface of the top layer, etching away the top layer to delineate lateral walls of bodies of the microcarriers, applying a continuous polymer layer over the top surface of the bodies of the microcarriers, removing the bottom layer and the insulating layer, structuring the bottom surfaces of the bodies of the microcarriers to define at least one three-dimensional structure on the bottom surface of each body, and removing the polymer layer to release the microcarriers.
申请公布号 US9333501(B2) 申请公布日期 2016.05.10
申请号 US201314414513 申请日期 2013.07.22
申请人 MYCARTIS NV 发明人 Demierre Nicolas;Gamper Stephan;Tornay Raphael;Renaud Philippe
分类号 B01L3/00;G01N15/14 主分类号 B01L3/00
代理机构 Kusner & Jaffe 代理人 Kusner & Jaffe
主权项 1. A method for producing microcarriers, the method comprising the following steps: (a) providing a wafer having a sandwich structure comprising a bottom layer, a top layer and an insulating layer located between said bottom and top layers, (b) structuring the top layer to define at least one three-dimensional structure on a top surface of the top layer, (c) etching away the top layer to delineate lateral walls of bodies of the microcarriers, each body comprising at least one three-dimensional structure on its top surface, (d) applying a continuous polymer layer over the top surface of the bodies of the microcarriers, (e) removing the bottom layer and the insulating layer, (f) structuring the bottom surfaces of the bodies of the microcarriers to define at least one three-dimensional structure on the bottom surface of each body, and (g) removing the polymer layer to release the microcarriers.
地址 Zwijnaarde/Ghent BE
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