发明名称 |
Topical therapeutic formulations |
摘要 |
The invention provides topical compositions and methods for using the compositions. The compositions can be used for the treatment of fibrotic or connective tissue disorders involving scarring, sub-dermal plaque accumulations, or fibrosis of muscle tissue. The disorders can be painlessly treated by the topical application of a composition described herein. One or more calcium channel blocker agents can serve as an active ingredient of the compositions, optionally in combination with, for example, one or more of emu oil and superoxide dismutase. The composition can further include pharmaceutically acceptable carriers that can facilitate the non-invasive transdermal delivery of the active(s) to subdermal sites. |
申请公布号 |
US9333242(B2) |
申请公布日期 |
2016.05.10 |
申请号 |
US201313747151 |
申请日期 |
2013.01.22 |
申请人 |
Hybrid Medical, LLC |
发明人 |
Twidwell Jeff;Buckley Joel;Hoium Harold |
分类号 |
A61K31/4422;A61K38/44;A61K31/4418;C07D211/90;A61K31/277;A61K31/40;A61K31/554;A61K9/00;A61K47/24;A61K9/06;A61K9/12 |
主分类号 |
A61K31/4422 |
代理机构 |
Schwegman Lundberg & Woessner, P.A. |
代理人 |
Schwegman Lundberg & Woessner, P.A. |
主权项 |
1. A transdermal gel composition suitable for topical application to the skin comprising 15 wt. to 30 wt. % of nicardipine, 0.1 wt. % to 2 wt. % of superoxide dismutase, and 60 wt. % to 85 wt. % of emu oil by weight in the total composition, and one or more pharmaceutically acceptable carriers or gelling agents. |
地址 |
Eden Prairie MN US |