A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFORE

摘要

The present disclosure relates to systems and methods for analyzing chromosomal translocations, and in particular to analysis of chromosomal translocation by in situ hybridization. The method employs a 5 '-probe, a 3 '-probe and a probe binding adjacent to, optionally overlapping, the breakpoint. The probes are differently labelled. In particular, the use in the detection of translocations involving the ALK gene are described.