发明名称 Controlled release levetiracetam formulations and methods for producing the same
摘要 Pharmaceutical compositions in the form of tablets are disclosed including water-soluble active ingredients such as levetiracetam and a polymer component which primarily includes water-insoluble polymers comprising between 60% and 100% of the polymer component in the tablet core, preferably the entire polymer component in the tablet core. The pharmaceutical compositions can also include an extended-release coating including both water-soluble and water-insoluble polymers.
申请公布号 US9333175(B2) 申请公布日期 2016.05.10
申请号 US201012816620 申请日期 2010.06.16
申请人 Mylan Inc. 发明人 Murty Mummini Aruna;Li Boyong
分类号 A61K9/20;A61K9/22;A61K9/28;A61K31/4015 主分类号 A61K9/20
代理机构 Lerner David Littenberg Krumholz & Mentlik 代理人 Lerner David Littenberg Krumholz & Mentlik
主权项 1. A pharmaceutical composition in the form of a tablet comprising a compressed tablet core comprising a water-soluble active ingredient comprising levetiracetam and a polymer component consisting essentially of a water-insoluble polymer comprising from between about 1 and 50 wt. % of said compressed tablet core, and comprising substantially the only polymer in said compressed tablet core, such that said compressed tablet core is free of any water-soluble polymer.
地址 Canonsburg PA US